In trial SAKK 01/10 we have investigated a new therapeutic approach in the hope that it will prove just as effective, but will be tolerated much better than the conventional treatments.

Conventional treatments for patients with a seminoma in stages IIA/B consist either of comprehensive radiotherapy or intensive chemotherapy with three different drugs. Both treatments prove successful in over 90% of patients, but unfortunately they are often associated with serious side effects. 

The new therapeutic approach is a combined treatment including, on the one hand, the administration of a drug used in the treatment of many different types of tumors and that is usually very well tolerated. On the other hand, the treatment also consists of radiotherapy targeted on the affected lymph nodes and which therefore manages with just a quarter of the radioactive exposure compared to traditional radiotherapy.